UMUC's Maryland Artist Collection is one of the largest and most comprehensive collections of 20th-century Maryland art in the state. Begun in 1978, the collection includes paintings, sculptures, prints, and photographs. The walls of UMUC's stateside headquarters in Adelphi offer the university an opportunity to celebrate and showcase the work of Maryland artists, and the rapid growth of the collection is a testament to the generosity and vitality of the many people supporting the visual arts in Maryland.

Among the highlights of the Maryland Artist Collection are large bodies of works by Baltimore artists Herman Maril, Gladys Goldstein, Selma L. Oppenheimer, and Raoul Middleman. The collection also has substantial holdings by artists Sy Gresser, William “Bill” Taylor, and Reini Maters. In 2010, UMUC opened the Leroy Merritt Center for the Art of Joseph Sheppard, a 5,500-square-foot structure housing permanent exhibitions of sculptures, paintings, and drawings by Maryland artist Joseph Sheppard. The center also features a study center with more than 2,000 art books.